Fig. 4.
Myomodulin increases burst robustness in an oscillator heart inter-neuron whose partner is voltage clamped. A: heart interneurons from ganglion 3 burst in alternation. 1: when the right neuron [HN(R,3)] was prevented from bursting by voltage clamp, the left neuron [HN(L,3)], recorded extracellularly, exhibited prolonged, irregular bursts; 2: when 1 μM myomodulin was added, the unclamped neuron maintained regular bursting while the partner neuron was voltage clamped. Robust bursting in the presence of myomodulin (MM) was indicated by a decrease in the coefficient of variation of period (B) and a decrease in burst duration (C).