Fig. 1.
Myomodulin changes the burst characteristics of oscillator heart interneurons. A: example extracellular recordings from heart interneurons in ganglion 3: HN(L,3) and HN(R,3). Period is measured as the time between median spikes (diamonds) of consecutive bursts. Burst duration is measured as the time from first to last spike in a burst. Before myomodulin application (1), HN(R,3) burst period was 10.2 s and mean intraburst spike frequency was 10.6 Hz. When 1 μM myomodulin was added (2), HN(R,3) period decreased to 7.4 s and mean spike frequency increased to 12.7 Hz. B: myomodulin decreased burst period while increasing mean, maximum, and minimum intraburst spike frequencies. * indicates significant difference from 0.